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Akila, P.
- A Retrospective Analysis of Serial Measurement of Serum Cholinesterase in Acute Poisoning with Organophosphate Compounds
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Toxicology International (Formerly Indian Journal of Toxicology), Vol 19, No 3 (2012), Pagination: 255-259Abstract
Objectives: Retrospective analysis of the utility of serial measurements of serum acetylcholinesterase (AChE) in predicting the duration of stay in the intensive care unit (ICU), duration of mechanical ventilation (MV) and outcome of the patient from MV in organophosphate (OP) compound poisoning patients. Materials and Methods: The medical records of patients who presented to tertiary care hospital with symptomatic insecticidal poisoning from January 2009 to December 2010 were utilized for the study purpose. Forty four patients with history of poisoning were admitted during this period. Out of these 37 patients with history of OP poisoning, without any underlying diseases and whose serial AChE activity levels were available were included in the study. Data regarding clinical manifestation at presentation, AChE activity results and its interpretation, details of patient management and data on outcomes of patients were noted. Results: Serum acetycholinesterase levels below 1,250IU/L, 1,789IU/L and 2,764IU/L on day three, day four and five respectively indicates longer duration of stay in the ICU. Patients with serum AChE levels below 975IU/L, 876IU/L, 1,245IU/L, 1,395IU/L and 1,875IU/L on day one, two, three, four and five respectively take a longer time to be out of mechanical ventilation. Levels below 870IU/L, 1,110IU/L, 1,020IU/L and 885IU/L on day two, three, four and five respectively indicate poor prognosis of the patient and mortality. Conclusion: We conclude that the serial measurements of serum acetylcholinesterase levels can be useful in predicting the length of ICU stay, duration of mechanical ventilation and the prognosis of the patient with OP poisoning.Keywords
Mechanical ventilation, organophosphate compound, retrospective analysis, serum acetylcholinesterase levels- Preliminary Photochemical Analysis of Elytraria acaulis (Lf) Lindau
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1 PG and Research, Department of Botany, Vellalar College for Women (Autonomous), Erode – 638012, Tamil Nadu, IN
1 PG and Research, Department of Botany, Vellalar College for Women (Autonomous), Erode – 638012, Tamil Nadu, IN
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ScieXplore: International Journal of Research in Science, Vol 7, No 1-2 (2020), Pagination: 47-51Abstract
A qualitative study to evaluate the phytochemical constituents in aqueous and methanol leaf extracts of Elytraria acaulis was done by following standard qualitative phytochemical screening methods. The prelimininary phytochemical analysis of Elytraria acaulis leaves showed the presence of carbohydrates, protein, alkaloids, tannins, glycosides, terpenoids, phenols, flavanoids, steroids and saponins in both the extracts compared to aqueous extract where saponins, steroids, alkaloids and carbohydrates were absent. The leaves of Elytraria acaulis might ensure phyto constituents source with stable, biologically active components that can establish a scientific base for synthesis modern medicine in future.Keywords
Acanthaceae, Elytraria acaulis, Flavanoids, Phytochemical Screening, Saponin and Anti Inflamatory, Tannins.References
- Ashok PK. Tannins are astringent. J. Pharmacogn. Phytochem. 2012; 1(3):45–50.
- Babu PS, Babu KA, Chitra K, Chamundeeshwari D. A review on phytochemical and pharmacological profile of Elytraria acaulis Lindau. Int J Pharm Sci Res. 2015; 6(9):3671–5.
- Bibitha BJ, Jisha VK, Salitha CV, Mohan S, Valsa AK. Antibacterial activity of different plant extracts, short communication. Indian Journal of Microbiology. 2002; 42:361–3.
- Dai J, Mumper RJ. Plant phenolics: Extraction, analysis and their antioxidant Elytraria acaulis. Adv Anim Vet Sci. 2014; 2(8):457–63. https://doi.org/10.14737/journal. aavs/2014/2.8.457.463
- Jagadeesan K, Thooyavan, Mullai Nila, Ilayaraja T. Studies on the anthelmintic and antioxidant activity of root extracts of Elytraria acaulis. Adv Anim Vet Sci. 2014: 2(8): 457–63.
- Just M, Recio MC, Giner RM, Cuellar MJ, Manez S, Bilia AR, et al. Anti-inflammatory activity of unusual lupane saponins from Bupleurum fruticescens. Planta Med. 1998; 64(5):404–7.
- Maghrani M, Zeggwah N, Michel J, Eddouks M. Antihypertensive effect of Lepidium sativum in spontaeneously hypertensive rats. J Ethnopharm. 2005; 102(1-2):193–7. PMid: 15955648. https://doi.org/10.1016/j.jep.2005.02.024
- Das MP, Jayanthi Rebecca L, Sharmila S. Evaluation of antibacterial and anti-fungal efficiency of Weddelia chinesis leaf extract. Journal of Chem Pharm RCS. 2013: 5(2):265–9.
- Panche AN, Diwan AD, Chandra SR. Flavonoids: an overview. J Nutr Sci. 2016; 5:47. PMid: 28620474 PMCid: PMC5465813. https://doi.org/10.1017/jns.2016.41
- Ravikanth V, Ramesh P, Diwan PV, Venkateswarlu Y. Pyrazole alkaloids from Elytrari aacaulis. Biochem Syst Eco. 2001; 29(7):753–4. https://doi.org/10.1016/S0305-1978(00)00109-5
- Sathish Babu P, Anand Babu K, Chitra K, Chamumdeeshwari D. A review of phytochemical and pharmacological profile of Elytraria acaulis LINDAU. IJPSR. 2015: 6(9):3671–5.
- Singh S, Nigam R, Sharma A, Kumar A, Laxmi V. Preliminary phytochemical screening of Elytraria acaulis roots. International Journal of Pharmaceutical Research. 2021; 33(4):1–9. https://doi.org/10.9734/jpri/2021/v33i431165
- Soobrattee MA, Neergheen VS, Luximon-Ramma A, Aruoma OI, Bahorun T. Steroidal saponins from Paris polyphylla. Phytomedicine. 2010; 17(14):1102–1.
- Soobrattee MA, Neergheen VS, Luximon-Ramma A, Aruoma OI, Bahorun T. Phenolics as potential anti-oxidant therapeutic agents: Mechanisms and actions. Mutat Res. 2005; 579:200–13. https://doi.org/10.1016/j.mrfmmm.2005.03.023
- Sundar S, Joseph LH, Raj TLS. Preliminary phytochemical and antimicrobial investigations of Elytrari aacaulis (L.F.) Lindau. Eur J Mol Biol Biochem. 2015; 2(2):71–4.
- Suresh Babu B, Lakshmi Narasu M, Venkanna B, Ashwitha K, Kalyani Narmada, CH. Evaluation of antimicrobial and antoxidative activities of the aerial plant extracts of Elytraria acaulis. Int J Curr Microbiol App Sci. 2016; 5(8):20–9. https://doi.org/10.20546/ijcmas.2016.508.003
- Suthama Raj RV. Primary phytochemical investigation of Sphagneticola trilobata (L) puruski. Journal of Pharmacognosy and Phytochemistry. 2019: 8(1):968–71.
- Wang GX, Han J, Zhao LW, Jiang DX, Liu YT, Liu XL. Anthelmintic activity of unusual lupine saponins from Bupleurum fruticescen. Planta Med. 2010; 64(05):404–7.